StratGG

Slay the Spire 2 Powers

Browse power effects with filters for type and stacking behavior.

Frequently Asked Questions

Core Combat Powers

Universal buffs and debuffs that affect every character — click to jump to its full entry.

253
Strength

Strength

Buff Intensity

Strength adds additional damage to Attacks.

Inflame, Brand, Fight Me, Dominate, Brimstone, Red Skull, Malaise, Bulk Up, Shared Fate, Friendship, Resonance, Mini Regent, Prowess, Mad Science, Vajra, Girya, Shuriken, Sling of Courage, Sparkling Rouge, Rainbow Ring, Philosopher's Stone, Toasty Mittens, Sword of Jade, Ember Tea, Strength Potion, Potions, Fysh Oil, The Lost, The Insatiable, Fogmog, The Adversary Mk 1, The Adversary Mk 2, The Adversary Mk 3, Ovicopter, Flail Knight, Nibbit, Myte, Mysterious Knight, Mecha Knight, Exoskeleton, Entomancer, Doormaker, Louse Progenitor, Living Shield, Door, Wriggler, Snapping Jaxfruit, Decimillipede, Lagavulin Matriarch, Slumbering Beetle, Sludge Spinner, Knowledge Demon, Vantom, Cubex Construct, Slimed Berserker, Kin Priest, Skulking Colony, Crusher, Kin Follower, Sewer Clam, Seapunk, Turret Operator, Scroll of Biting, Infested Prism, Ceremonial Beast, Rocket, Queen, Gremlin Merc, Axebot, Globe Head, Bygone Effigy, Phantasmal Gardener, Brute Raider, Fuzzy Wurm Crawler, The Obscura, Frog Knight, Bowlbug (Nectar)
Negative Strength is possible.
Dexterity

Dexterity

Buff Intensity

Dexterity improves Block gained from cards.

Abrasive, Footwork, Bulk Up, Prowess, Belt Buckle, Sparkling Rouge, Kunai, Oddly Smooth Stone, Rainbow Ring, Fysh Oil, Potions, Dexterity Potion, The Forgotten, Lagavulin Matriarch
Artifact

Artifact

Buff Counter

Negates debuffs.

The Adversary Mk Two, The Adversary Mk Three, Cubex Construct, Punch Construct, Chomper, Mecha Knight
Block Next Turn

Block Next Turn

Buff Intensity

At the start of your next turn, gain 4 Block.

Dodge and Roll, Glitterstream, Prolong, Ship in a Bottle, Potions
Draw Cards Next Turn

Draw Cards Next Turn

Buff Intensity

At the start of your next turn, draw 1 additional card.

Predator, Guiding Star, Relax
Energy Next Turn

Energy Next Turn

Buff Intensity

Gain additional Energy next turn.

Outmaneuver, Charge Battery, Scavenge, Delay, Invoke, Convergence, Refine Blade, Hegemony, Relax
Focus

Focus

Buff Intensity

Increases the effectiveness of Orbs.

Biased Cognition, Defragment, Hyperbeam, Data Disk, Focus Potion, Potions
Allows negative values.
Intangible

Intangible

Buff Duration

Reduce all damage taken and HP loss to 1 this turn.

Wraith Form, Eidolon, Apparition, Ghost in a Jar, Potions, Soul Fysh, Test Subject
Intangible is removed at the end of the enemy turn. The damage cap is raised to 5 if the attacker has The Boot.
Plating

Plating

Buff Intensity

At the end of your turn, gain Block. Plating is reduced by 1 at the start of your turn.

Stone Armor, Eternal Armor, Gorget, Heart of Iron, Potions, Neutron Aegis, Mysterious Knight, Lagavulin Matriarch, Slumbering Beetle, Sewer Clam, Frog Knight
On enemies, Plating decreases by 1 per player per turn.
Retain Hand

Retain Hand

Buff Duration

Retain your Hand for the next 2 turns.

Salvo, Equilibrium, Convergence, Stable Serum, Potions
Thorns

Thorns

Buff Intensity

When hit by an attack, deal damage back.

Abrasive, Caltrops, Bronze Scales, Liquid Bronze, Potions, Spiny Toad, Toadpole
Vigor

Vigor

Buff Intensity

Your next Attack deals additional damage.

Terraforming, Patter, Akabeko, Terror Eel
Buffer

Buffer

Buff Counter

Prevent the next time you would lose HP.

Buffer, Lucky Tonic, Potions
Clarity

Clarity

Buff Duration

At the start of your next turn, draw 1 additional card.

Clarity Extract, Potions
Diamond Diadem

Diamond Diadem

Buff Does not stack

Enemies deal 50% less damage this turn.

Diamond Diadem
Duplication

Duplication

Buff Counter

Your next card is played an extra time.

Duplicator, Potions
Flex Potion

Flex Potion

Buff Intensity

Gain Strength until the end of this turn.

Flex Potion, Potions
Temporary Strength Mechanically identical to Reptile Trinket, Setup Strike, Coordinate, and Feeding Frenzy
Gigantification

Gigantification

Buff Counter

The next Attack you play deals triple damage.

Gigantification Potion, Potions
Radiance

Radiance

Buff Duration

Gain an additional Energy next turn.

Radiant Tincture, Potions
Regen

Regen

Buff Intensity

Regen heals HP at the end of your turn. Each turn, Regen is reduced by 1.

Regen Potion, Potions
Reptile Trinket

Reptile Trinket

Buff Intensity

Gain Strength until the end of this turn.

Reptile Trinket
Temporary Strength gained when a Potion is used. Mechanically identical to Flex Potion, Setup Strike, Coordinate, and Feeding Frenzy
Ritual

Ritual

Buff Intensity

Gain Strength at the end of your turn.

Mazaleth's Gift, Potions, Devoted Sculptor, Damp Cultist, Calcified Cultist
Skips the first end-of-turn trigger when applied by an enemy.
Speed Potion

Speed Potion

Buff Intensity

Gain Dexterity until the end of this turn.

Speed Potion, Potions
Temporary Dexterity Mechanically identical to Anticipate and Helical Dart
Aggression

Aggression

Buff Intensity

At the start of your turn, put a random Attack from your Discard Pile into your Hand and Upgrade it for the rest of combat.

Aggression
Barricade

Barricade

Buff Does not stack

Block is not removed at the start of your turn.

Barricade
Colossus

Colossus

Buff Duration

You receive 50% less damage from Vulnerable enemies this turn.

Colossus
Corruption

Corruption

Buff Does not stack

Skills cost 0.
Whenever you play a Skill, Exhaust it.

Corruption
Crimson Mantle

Crimson Mantle

Buff Intensity

At the start of your turn, lose HP and gain Block.

Crimson Mantle
Self-damage increases each time Crimson Mantle is applied.
Cruelty

Cruelty

Buff Intensity

Vulnerable enemies take additional damage.

Cruelty
Dark Embrace

Dark Embrace

Buff Intensity

Whenever a card is Exhausted, draw 1 card.

Dark Embrace
Demon Form

Demon Form

Buff Intensity

At the start of your turn, gain 2 Strength.

Demon Form
Drum of Battle

Drum of Battle

Buff Intensity

At the start of your turn, Exhaust the top 2 cards of your Draw Pile.

Drum of Battle
Feel No Pain

Feel No Pain

Buff Intensity

Whenever a card is Exhausted, gain 3 Block.

Feel No Pain
Flame Barrier

Flame Barrier

Buff Intensity

Whenever you are attacked this turn, deal 4 damage back.

Flame Barrier
Free Attack

Free Attack

Buff Counter
Your next Attack costs 0 energy.
Unrelenting
Guarded

Guarded

Buff Does not stack

Take half damage from enemies.

Tank
Applied to allies by the Tank power. The Tank player takes double damage instead.
Hellraiser

Hellraiser

Buff Does not stack

Whenever you draw a card containing "Strike", it is played against a random enemy.

Hellraiser
Inferno

Inferno

Buff Intensity

At the start of your turn, lose 1 HP. Whenever you lose HP on your turn, deal 4 damage to ALL enemies.

Inferno
Self-damage increases by 1 each time Inferno is applied.
Juggernaut

Juggernaut

Buff Intensity

Whenever you gain Block, deal 5 damage to a random enemy.

Juggernaut
Juggling

Juggling

Buff Intensity

Add a copy of the third Attack you play each turn into your Hand.

Juggling
The copy counter resets each turn.
One-Two Punch

One-Two Punch

Buff Counter

Your next Attack is played an extra time this turn.

One-Two Punch
Removed at end of turn.
Pyre

Pyre

Buff Intensity

Gain 1 Energy at the start of each turn.

Pyre
Rage

Rage

Buff Intensity

Whenever you play an Attack this turn, gain 3 Block.

Rage
Removed at end of turn.
Rupture

Rupture

Buff Intensity

Whenever you lose HP on your turn, gain 1 Strength.

Rupture
HP loss from cards you play is batched and applied after the card resolves.
Self-Forming Clay

Self-Forming Clay

Buff Counter

Gain 3 Block next turn.

Self-Forming Clay
Triggers when your Block is cleared (reduced to 0). Removed after triggering.
Setup Strike

Setup Strike

Buff Intensity

Gain Strength until the end of this turn.

Setup Strike
Temporary Strength Mechanically identical to Flex Potion, Reptile Trinket, Coordinate, and Feeding Frenzy
Stampede

Stampede

Buff Intensity

At the end of your turn, 1 random Attack in your Hand is played against a random enemy.

Stampede
Tank

Tank

Buff Does not stack

Take double damage from enemies. Allies take half damage from enemies.

Tank
Unmovable

Unmovable

Buff Intensity

The first time you gain Block from a card each turn, double the amount gained.

Unmovable
Vicious

Vicious

Buff Intensity

Whenever you apply Vulnerable, draw 1 card.

Vicious
Accelerant

Accelerant

Buff Intensity

Poison is triggered an additional time.

Accelerant
Accuracy

Accuracy

Buff Intensity

Shivs deal additional damage.

Accuracy
Afterimage

Afterimage

Buff Intensity

Whenever you play a card, gain 1 Block.

Afterimage
Anticipate

Anticipate

Buff Intensity

Gain Dexterity until the end of this turn.

Anticipate
Temporary Dexterity Mechanically identical to Speed Potion and Helical Dart
Blade of Ink

Blade of Ink

Buff Intensity

Whenever you play an Attack this turn, gain 2 Strength this turn.

Blade of Ink
Blur

Blur

Buff Duration

Block is not removed at the start of your next turn.

Blur
Burst

Burst

Buff Counter

This turn, your next Skill is played an extra time.

Burst
Removed at end of turn.
Corrosive Wave

Corrosive Wave

Buff Intensity

Whenever you draw a card this turn, apply 2 Poison to ALL enemies.

Corrosive Wave
Double Damage

Double Damage

Buff Duration

This turn, Attacks deal double damage.

Shadow Step
Envenom

Envenom

Buff Intensity

Whenever you deal unblocked attack damage, apply 1 Poison.

Envenom
Fan of Knives

Fan of Knives

Buff Does not stack

Shivs hit ALL enemies.

Fan of Knives
Free Skill

Free Skill

Buff Counter
The next Skill you play costs 0 energy.
Pounce
Helical Dart

Helical Dart

Buff Intensity

Gain Dexterity until the end of this turn.

Helical Dart
Temporary Dexterity Gained when a Shiv is played. Mechanically identical to Speed Potion and Anticipate.
Infinite Blades

Infinite Blades

Buff Intensity

At the start of your turn, add a Shiv into your Hand.

Infinite Blades
Master Planner

Master Planner

Buff Does not stack

When you play a Skill, it gains Sly.

Master Planner
Nightmare

Nightmare

Buff Intensity

Add 3 of a chosen card into your Hand next turn.

Nightmare
Phantom Blades

Phantom Blades

Buff Intensity

Shivs gain Retain.
The first Shiv you play each turn deals 9 additional damage.

Phantom Blades
Serpent Form

Serpent Form

Buff Intensity

Whenever you play a card, deal 4 damage to a random enemy.

Serpent Form
Shadow Step

Shadow Step

Buff Intensity

Next turn, Attacks deal double damage.

Shadow Step
At the start of your turn, grants X Double Damage and is removed. It is possible to stack Shadow Step with Burst or Master Planner
Shadowmeld

Shadowmeld

Buff Counter

Double your Block gain this turn.

Shadowmeld
Removed at end of turn. Stacks multiplicatively (2^X multiplier).
Sneaky

Sneaky

Buff Intensity

Whenever another player attacks an enemy, gain Block.

Sneaky
Speedster

Speedster

Buff Intensity

Whenever you draw a card during your turn, deal 1 damage to ALL enemies.

Speedster
Only triggers on cards drawn outside the normal hand draw (e.g. from card effects).
The Hunt

The Hunt

Buff Intensity

Gain 1 additional card reward at the end of combat.

The Hunt
Tools of the Trade

Tools of the Trade

Buff Intensity

At the start of your turn, draw 1 card and discard 1 card.

Tools of the Trade
Tracking

Tracking

Buff Intensity

Weak enemies take 2 times more damage from Attacks.

Tracking
Well-Laid Plans

Well-Laid Plans

Buff Intensity

At the end of your turn, Retain up to 1 card.

Well-Laid Plans
Arsenal

Arsenal

Buff Intensity

Whenever you play a Colorless card, gain 1 Strength.

Arsenal
Black Hole

Black Hole

Buff Intensity
Whenever you spend or gain star, deal 3 damage to ALL enemies.
Black Hole
Child of the Stars

Child of the Stars

Buff Intensity
Gain 1 Block for each star spent.
Child of the Stars
Foregone Conclusion

Foregone Conclusion

Buff Intensity

Next turn, put 3 cards from your Draw Pile into your Hand.

Foregone Conclusion
Furnace

Furnace

Buff Intensity

At the start of your turn, Forge 5.

Furnace
Genesis

Genesis

Buff Intensity
At the start of your turn, gain star.
Genesis
Hammer Time

Hammer Time

Buff Does not stack

Whenever you Forge, all allies Forge as well.

Hammer Time
Monarch's Gaze

Monarch's Gaze

Buff Intensity

Whenever you attack an enemy, it loses 1 Strength this turn.

Monarch's Gaze
Monologue

Monologue

Buff Does not stack

Whenever you play a card this turn, gain 1 Strength this turn.
Currently granting 0 Strength.

Monologue
Removed at end of turn. Strength gained is also removed.
Orbit

Orbit

Buff Intensity

Every 4 Energy you spend, gain an Energy.

Orbit
Pale Blue Dot

Pale Blue Dot

Buff Intensity

If you play enough cards in a turn, draw additional cards at the start of your next turn.

Pale Blue Dot
Parry

Parry

Buff Intensity

Whenever you play Sovereign Blade, gain 8 Block.

Parry
Pillar of Creation

Pillar of Creation

Buff Intensity

Whenever you create a card, gain 5 Block.

Pillar of Creation
Reflect

Reflect

Buff Duration

Blocked damage is reflected to your attacker.

Reflect
Royalties

Royalties

Buff Intensity

At the end of combat, gain 25 Gold.

Royalties
Seeking Edge

Seeking Edge

Buff Does not stack

Sovereign Blade now hits ALL enemies.

Seeking Edge
Spectrum Shift

Spectrum Shift

Buff Intensity

At the start of your turn, add 1 random Colorless card into your Hand.

Spectrum Shift
Star Next Turn

Star Next Turn

Buff Intensity
Gain 1 star next turn.
Convergence, Hidden Cache
Removed after triggering.
Sword Sage

Sword Sage

Buff Intensity

Increase the cost of Sovereign Blade by 1. Sovereign Blade now hits 1 additional time.

Sword Sage
The Sealed Throne

The Sealed Throne

Buff Intensity
Whenever you play a card, gain star.
The Sealed Throne
Tyranny

Tyranny

Buff Intensity

At the start of your turn, draw a card and Exhaust a card from your Hand.

Tyranny
Void Form

Void Form

Buff Intensity

The first 2 cards you play each turn are free to play.

Void Form
Calcify

Calcify

Buff Intensity

Osty's attacks deal additional damage.

Calcify
Call of the Void

Call of the Void

Buff Intensity

At the start of your turn, add 1 random card into your Hand and apply Ethereal to it.

Call of the Void
Countdown

Countdown

Buff Intensity

At the start of your turn, apply 6 Doom to a random enemy.

Countdown
Danse Macabre

Danse Macabre

Buff Intensity

Whenever you play a card that costs 2 Energy or more, gain 7 Block.

Danse Macabre
Demesne

Demesne

Buff Intensity

At the start of your turn, gain 1 Energy and draw 1 additional card.

Demesne
Devour Life

Devour Life

Buff Intensity

Whenever you play a Soul, Summon 1.

Devour Life
Die for You

Die for You

Buff Does not stack

Osty absorbs all unblocked attack damage.

Innate to Osty
Forbidden Grimoire

Forbidden Grimoire

Buff Intensity

At the end of combat, remove a card from your Deck.

Forbidden Grimoire
Friendship

Friendship

Buff Intensity

Gain 1 Energy at the start of each turn.

Friendship
Haunt

Haunt

Buff Intensity

Whenever you play a Soul, a random enemy loses 3 HP.

Haunt
Lethality

Lethality

Buff Intensity

The first Attack each turn deals 50% additional damage.

Lethality
Necro Mastery

Necro Mastery

Buff Intensity

Whenever Osty loses HP, ALL enemies lose that much HP as well.

Necro Mastery
Pagestorm

Pagestorm

Buff Intensity

Whenever you draw an Ethereal card, draw 1 card.

Pagestorm
Reaper Form

Reaper Form

Buff Intensity

Whenever Attacks deal damage, they also apply that much Doom.

Reaper Form
Sentry Mode

Sentry Mode

Buff Intensity

At the start of your turn, add 1 Sweeping Gaze into your Hand.

Sentry Mode
Shroud

Shroud

Buff Intensity

Whenever you apply Doom, gain 3 Block.

Shroud
Sleight of Flesh

Sleight of Flesh

Buff Intensity

Whenever you apply a debuff to an enemy, they take 13 damage.

Sleight of Flesh
Does not trigger from temporary debuffs.
Spirit of Ash

Spirit of Ash

Buff Intensity

Whenever you play an Ethereal card, gain 4 Block.

Spirit of Ash
Summon Next Turn

Summon Next Turn

Buff Intensity

At the start of your next turn, Summon 2.

Invoke
Removed after triggering.
Veilpiercer

Veilpiercer

Buff Counter

The next Ethereal card you play costs 0.

Veilpiercer
Consuming Shadow

Consuming Shadow

Buff Intensity

At the end of your turn, Evoke your leftmost Orb.

Consuming Shadow
Coolant

Coolant

Buff Intensity

At the start of your turn, gain 3 Block for each unique Orb you have.

Coolant
Creative AI

Creative AI

Buff Intensity

At the start of your turn, add a random Power into your Hand.

Creative AI
Echo Form

Echo Form

Buff Intensity

The first card you play each turn is played an extra time.

Echo Form
Feral

Feral

Buff Intensity
The first time you play a 0energy Attack each turn, return it to your Hand.
Feral
Focused Strike

Focused Strike

Buff Intensity

Gain Focus until the end of this turn.

Focused Strike
Temporary Focus Mechanically identical to Hotfix and Synchronize
Free Power

Free Power

Buff Counter
The next Power you play costs 0 energy.
Synthesis
Hailstorm

Hailstorm

Buff Intensity

At the end of your turn, if you have Frost, deal 6 damage to ALL enemies.

Hailstorm
Hello World

Hello World

Buff Intensity

At the start of your turn, add 1 random Common card into your Hand.

Hello World
Hotfix

Hotfix

Buff Intensity

Gain Focus until the end of this turn.

Hotfix
Temporary Focus Mechanically identical to Focused Strike and Synchronize
Iteration

Iteration

Buff Intensity

The first time you draw a Status card each turn, draw more cards.

Iteration
Lightning Rod

Lightning Rod

Buff Duration

At the start of the next 2 turns, Channel 1 Lightning.

Lightning Rod
Loop

Loop

Buff Intensity

At the start of your turn, trigger the passive ability of your next Orb.

Loop
Machine Learning

Machine Learning

Buff Intensity

At the start of your turn, draw 1 additional card.

Machine Learning
Rebound

Rebound

Buff Counter

The next card you play this turn is placed on the top of your Draw Pile.

Rebound
Removed at end of turn.
Signal Boost

Signal Boost

Buff Counter

Your next Power is played an extra time.

Signal Boost
Loses 1 stack each time a Power is played an extra time.
Smokestack

Smokestack

Buff Intensity

Whenever you create a Status, deal damage to ALL enemies.

Smokestack
Spinner

Spinner

Buff Intensity

At the start of your turn, Channel 1 Glass.

Spinner
Storm

Storm

Buff Intensity

Whenever you play a Power, Channel 1 Lightning.

Storm
Subroutine

Subroutine

Buff Intensity
Whenever you play a Power, gain 1 energy.
Subroutine
Synchronize

Synchronize

Buff Intensity

Gain Focus until the end of this turn.

Synchronize
Temporary Focus Mechanically identical to Focused Strike and Hotfix
Thunder

Thunder

Buff Intensity

Whenever you Evoke Lightning, deal 8 damage to each enemy hit.

Thunder
Trash to Treasure

Trash to Treasure

Buff Intensity

Whenever you create a Status, Channel 1 random Orb.

Trash to Treasure
Automation

Automation

Buff Intensity

Every 10 cards you draw, gain Energy.

Automation
Beacon of Hope

Beacon of Hope

Buff Intensity

Whenever you gain Block on your turn, other players gain half that much Block.

Beacon of Hope
Calamity

Calamity

Buff Intensity

Whenever you play an Attack, add a random Attack into your Hand.

Calamity
Coordinate

Coordinate

Buff Intensity

Gain Strength until the end of this turn.

Coordinate
Temporary Strength Mechanically identical to Flex Potion, Reptile Trinket, Setup Strike, and Feeding Frenzy
Covered

Covered

Buff Does not stack

An ally is covering you. All attacks that would be directed to you are redirected to them instead.

Intercept
Curious

Curious

Buff Intensity
Powers cost 1 energy less.
Mad Science
Entropy

Entropy

Buff Intensity

At the start of your turn, Transform 1 card in your Hand.

Entropy
Fasten

Fasten

Buff Intensity

Gain an additional 4 Block from Defend cards.

Fasten
Feeding Frenzy

Feeding Frenzy

Buff Intensity

Gain Strength until the end of this turn.

Feeding Frenzy
Temporary Strength Mechanically identical to Flex Potion, Reptile Trinket, Setup Strike, and Feeding Frenzy
Improvement

Improvement

Buff Intensity

At the end of combat, Upgrade a random card.

Mad Science
Intercept

Intercept

Buff Does not stack

You are covering . All attacks that would be directed towards them are redirected towards you.

Intercept
Multiplayer only. Damage taken is multiplied by the number of players covered + 1. Removed at the end of the enemy turn.
Mayhem

Mayhem

Buff Intensity

At the start of your turn, play the top card of your Draw Pile.

Mayhem
Nostalgia

Nostalgia

Buff Intensity

The first Attack or Skill you play each turn is placed on top of your Draw Pile.

Nostalgia
Panache

Panache

Buff Intensity

If you play 5 cards this turn, deal damage to ALL enemies.

Panache
Counter resets to 5 each turn. Displayed amount shows cards remaining, not power stacks.
Prep Time

Prep Time

Buff Intensity

At the start of your turn, gain 4 Vigor.

Prep Time
Rolling Boulder

Rolling Boulder

Buff Intensity

At the start of your turn, deal 5 damage to ALL enemies and increase this damage by 5.

Rolling Boulder
Stratagem

Stratagem

Buff Intensity

Whenever you shuffle your Draw Pile, choose 1 card from it to put into your Hand.

Stratagem
Singleplayer only.
The Bomb

The Bomb

Buff Duration

At the end of 3 turns, deal 40 damage to ALL enemies.

The Bomb
Toric Toughness

Toric Toughness

Buff Duration

Gain 5 Block at the start of the next 2 turns.

Toric Toughness
Adaptable

Adaptable

Buff Does not stack

When this creature would be defeated, it instead revives even stronger.

Test Subject
Asleep

Asleep

Buff Duration

TODO

Lagavulin Matriarch
Back Attack

Back Attack

Buff Does not stack

Deals 50% more damage when it is attacking you from behind.

Crusher
Burrowed

Burrowed

Buff Does not stack

Block is not removed at the start of this creature's turn. Stunned if all Block is removed.

Tunneler
Loses all Block when Burrowed is removed.
Crab Rage

Crab Rage

Buff Does not stack

When an ally dies, this creature gains 5 Strength and 99 Block.

Rocket, Crusher
Curl Up

Curl Up

Buff Intensity

When damaged, rolls up and gains block. (Once per combat)

Louse Progenitor
Enrage

Enrage

Buff Intensity

Whenever you play a Skill, gains 2 Strength.

Test Subject
Escape Artist

Escape Artist

Buff Duration

Exits the combat after 4 turns.

Thieving Hopper
Flutter

Flutter

Buff Intensity

Receives 50% less damage from Attacks.

Thieving Hopper
Galvanic

Galvanic

Buff Intensity

Powers are afflicted with .

Globe Head
Applied innately by Globe Head at combat start. Afflicts all Power-type cards with the Galvanized affliction, which deals damage to the card's owner when played.
Gravity

Gravity

Buff Intensity

Whenever you play a card this turn, deal 2 damage to ALL enemies.

No known sources found in cards, relics, potions, or monsters. May be granted by an event or other mechanism.
Hard to Kill

Hard to Kill

Buff Intensity

Reduce all damage taken and HP lost by this creature to 9.

Exoskeleton
Applied innately by Exoskeleton. Caps all damage instances to 9.
Hardened Shell

Hardened Shell

Buff Intensity

This creature cannot lose more than 20 HP each turn.

Skulking Colony
Applied innately by Skulking Colony. Damage cap resets at the start of each player turn.
Hatch

Hatch

Buff Duration

Hatches after X turns.

Tough Egg
Heist

Heist

Buff Intensity

When killed, returns all the stolen Gold.

Gremlin Merc
Applied to Fat Gremlin when Gremlin Merc dies (via Surprise power). Killing the Fat Gremlin returns stolen gold.
High Voltage

High Voltage

Buff Intensity

At the start of this creature's turn, it gains 2 Strength.

Zapbot
Applied innately by Zapbot.
Illusion

Illusion

Buff Does not stack

When this dies, it revives next turn at full HP.

Parafright, Eye With Teeth
Infested

Infested

Buff Does not stack

Upon dying, summons... something.

Phrog Parasite
Spawns 4 Wrigglers on death.
Leadership

Leadership

Buff Intensity

All other allies deal 1 additional damage.

TBC
Minion

Minion

Buff Does not stack

Minions abandon combat without their leader.

Ovicopter, Fabricator, Kin Follower, Torch Head Amalgam, Gas Bomb
Nemesis

Nemesis

Buff Does not stack

At the end of every other turn, gains Intangible 1.

Test Subject
Painful Stabs

Painful Stabs

Buff Intensity

Shuffle 1 Wound into your Discard Pile each time you receive unblocked attack damage.

Test Subject
Paper Cuts

Paper Cuts

Buff Intensity

Whenever this creature deals unblocked attack damage to you, you lose 1 Max HP.

Scroll of Biting
Personal Hive

Personal Hive

Buff Intensity

Whenever this enemy is hit by an Attack, add Dazed into your Draw Pile.

Entomancer
Possess Speed

Possess Speed

Buff Does not stack

When killed, return all stolen Dexterity to the player.

The Forgotten
Possess Strength

Possess Strength

Buff Does not stack

When killed, return all stolen Strength to the player.

The Lost
Rampart

Rampart

Buff Intensity

At the start of the player's turn, Turret Operator gains 25 Block.

Living Shield
Ravenous

Ravenous

Buff Intensity

When an enemy dies, Corpse Slug immediately eats it, becoming Stunned and gaining 1 Strength.

Corpse Slug
Reattach

Reattach

Buff Does not stack

If other segments are still alive, revives in 2 turns with 25 HP.

Decimillipede
Sandpit

Sandpit

Buff Duration

A power used by The Insatiable.

The Insatiable
Applied to the player. Counts down each enemy turn. If it reaches 0, the player is killed.
Skittish

Skittish

Buff Intensity

The first time this creature is hit each turn, it gains 1 Block.

Phantasmal Gardener
Only triggers once per turn. Resets at end of turn.
Slippery

Slippery

Buff Counter

The next time this creature loses HP, it only loses 1 HP instead.

Vantom, Inklet
Loses 1 stack each time it takes damage.
Slumber

Slumber

Buff Counter

Awakens upon taking turns or losing HP 3 times.

Slumbering Beetle
Loses stacks from both taking damage and enemy turns ending. When removed, the Slumbering Beetle wakes up.
Soar

Soar

Buff Does not stack

Receives 50% less attack damage until it lands.

Owl Magistrate
Only reduces damage from powered attacks. Does not stack.
Steam Eruption

Steam Eruption

Buff Intensity

When killed, deals damage at the end of your next turn.

Waterfall Giant
Innate to Waterfall Giant. Accumulated through its moves. On death, the Giant becomes Stunned, then explodes for the full accumulated amount.
Stock

Stock

Buff Intensity

When killed, a new Axebot is summoned in its place.

Axebot
The new Axebot spawns with Stock reduced by 1. At 0, no further Axebots spawn.
Suck

Suck

Buff Intensity

Whenever this creature deals unblocked attack damage, it gains 1 Strength.

Fossil Stalker
Innate to Fossil Stalker.
Surprise

Surprise

Buff Does not stack

Something is off about this creature...

Gremlin Merc
When Gremlin Merc dies, a Sneaky Gremlin and Fat Gremlin are spawned.
Swipe

Swipe

Buff Does not stack

Upon killing this enemy, the stolen card is returned.

Thieving Hopper
Applied by Thieving Hopper when it steals a card. Each stolen card is a separate instance of Swipe.
Territorial

Territorial

Buff Intensity

At the end of its turn, gains 1 Strength.

Byrdonis
Thievery

Thievery

Buff Intensity

Steals Gold when Attacking.

Gremlin Merc
Time Limit

Time Limit

Buff Duration

You have 3 more turns to defeat the Battleworn Dummy.

Battle Friend V1.0, Battle Friend V2.0, Battle Friend V3.0
Vital Spark

Vital Spark

Buff Intensity
The first time this creature takes Attack damage each turn, the attacker gains energy.
Infested Prism
Vulnerable

Vulnerable

Debuff Duration

Vulnerable creatures take 50% more damage from Attacks.

Bash, Break, Molten Fist, Taunt, Thunderclap, Tremble, Uppercut, Assassinate, Expose, Beam Cell, Fear, High Five, Putrefy, Comet, Falling Star, Gamma Blast, Know Thy Place, Meteor Shower, Mad Science, Shockwave, Squash, Bag of Marbles, Hand Drill, Vulnerable Potion, Potions, Potion of Binding, Flyconid, Haunted Ship, Mawler, Ovicopter, Owl Magistrate, Queen, Soul Fysh, Soul Nexus, Terror Eel, Test Subject
Weak

Weak

Debuff Duration

Weakened creatures deal 25% less damage with Attacks.

Uppercut, Follow Through, Leg Sweep, Malaise, Neutralize, Sucker Punch, Suppress, Go for the Eyes, Null, Deathbringer, Defy, Putrefy, Comet, Falling Star, Gamma Blast, Know Thy Place, Meteor Shower, Mad Science, Shockwave, Red Mask, Weak Potion, Potions, Potion of Binding, Axebot, Bowlbug (Silk), Crusher, Decimillipede, Gremlin Merc, Haunted Ship, Kin Priest, Punch Construct, Queen, Slimed Berserker, Sludge Spinner, Soul Nexus, Waterfall Giant, (Self) Doubt
Frail

Frail

Debuff Duration

While Frail, gain 25% less Block from cards.

Axebot, Corpse Slug, Crusher, Fake Merchant Monster, Flyconid, Fossil Stalker, Frog Knight, Globe Head, Haunted Ship, Kin Priest, Louse Progenitor, Queen, Stabbot, Tracker Raider, Two-Tailed Rat, (Self) Shame
Poison

Poison

Debuff Intensity

Poisoned creatures lose HP at the start of their turn. Each turn, Poison is reduced by 1.

Bouncing Flask, Bubble Bubble, Corrosive Wave, Deadly Poison, Envenom, Haze, Noxious Fumes, Poisoned Stab, Snakebite, Twisted Funnel, Poison Potion, Potions
Doom

Doom

Debuff Intensity

At the end of the enemy turn, if it has at least as much Doom as HP, it dies.

Blight Strike, Deathbringer, End of Days, No Escape, Negative Pulse, Scourge, Potion of Doom, Potions, (Self) Borrowed Time
Confused

Confused

Debuff Does not stack

The costs of your cards are randomized on draw, from 0 to 3.

(Self) Snecko Eye, (Self) Snecko Eye???
Demise

Demise

Debuff Intensity

At the end of its turn, this creature X loses HP.

Powdered Demise, Potions
Shrink

Shrink

Debuff Duration

This creature's Attacks deal 30% less damage for the next 3 turns.

Shrinker Beetle, Beetle Juice, Potions
Shackling Potion

Shackling Potion

Debuff Intensity

Lose Strength until the end of this turn.

Piercing Wail
Temporary Strength loss Mechanically Identical to Mangle, Piercing Wail, Crush Under, Dying Star, Enfeebling Touch, Monarch's Gaze Strength Down, and Dark Shackles
Mangle

Mangle

Debuff Intensity

Lose Strength until the end of this turn.

Mangle
Temporary Strength loss Mechanically Identical to Shackling Potion, Piercing Wail, Crush Under, Dying Star, Monarch's Gaze Strength Down, and Enfeebling Touch, and Dark Shackles
Grapple

Grapple

Debuff Intensity

Whenever you gain Block this turn, deal 5 damage to the enemy.

Grapple
Flanking

Flanking

Debuff Intensity

Other allies deal 2x more damage to this enemy this turn.

Flanking
Multiplayer only.
Piercing Wail

Piercing Wail

Debuff Intensity

Lose Strength until the end of this turn.

Piercing Wail
Temporary Strength loss Mechanically Identical to Shackling Potion, Mangle, Crush Under, Dying Star, Enfeebling Touch, Monarch's Gaze Strength Down, and Dark Shackles
No Draw

No Draw

Debuff Does not stack

You may not draw any more cards this turn.

(Self) Battle Trance, (Self) Bullet Time
Strangle

Strangle

Debuff Intensity

Whenever you play a card this turn, this enemy loses 2 HP.

Strangle, Mad Science
Wraith Form

Wraith Form

Debuff Intensity

At the start of your turn, lose 1 Dexterity.

(Self) Wraith Form
Conqueror

Conqueror

Debuff Duration

Sovereign Blade deals double damage to the enemy this turn.

Conqueror
Crush Under

Crush Under

Debuff Intensity

Lose Strength until the end of this turn.

Crush Under
Temporary Strength loss Mechanically Identical to Shackling Potion, Mangle, Piercing Wail, Dying Star, Monarch's Gaze Strength Down, Enfeebling Touch, and Dark Shackles
Dying Star

Dying Star

Debuff Intensity

Lose Strength until the end of this turn.

Crush Under
Temporary Strength loss Mechanically Identical to Shackling Potion, Mangle, Piercing Wail, Crush Under, Monarch's Gaze Strength Down, Enfeebling Touch, and Dark Shackles
Monarch's Gaze Strength Down

Monarch's Gaze Strength Down

Debuff Intensity

Lose Strength until the end of this turn.

Monarch's Gaze
Temporary Strength loss Mechanically Identical to Shackling Potion, Mangle, Piercing Wail, Crush Under, Dying Star, Enfeebling Touch, and Dark Shackles
Debilitate

Debilitate

Debuff Duration

Vulnerable and Weak are twice as effective for the next 2 turns.

Debilitate
Enfeebling Touch

Enfeebling Touch

Debuff Intensity

Lose Strength until the end of this turn.

Enfeebling Touch
Temporary Strength loss Mechanically Identical to Shackling Potion, Mangle, Piercing Wail, Crush Under, Dying Star, Monarch's Gaze Strength Down, and Dark Shackles
Hang

Hang

Debuff Intensity

All Hangs deal 2 times more damage to this enemy.

Hang
Stacks multiplicatively (minimum +2 per application). Capped at 999.
Neurosurge

Neurosurge

Debuff Intensity

At the start of your turn, apply 3 Doom to yourself.

(Self) Neurosurge
Oblivion

Oblivion

Debuff Intensity

Whenever you play a card, this enemy gains 1 Doom.

Oblivion
Sic 'Em

Sic 'Em

Debuff Intensity

Whenever Osty hits this enemy this turn, Summon 3.

Sic 'Em
Biased Cognition

Biased Cognition

Debuff Intensity

At the start of your turn, lose 1 Focus.

(Self) Biased Cognition
Dark Shackles

Dark Shackles

Debuff Intensity

Lose Strength until the end of this turn.

Dark Shackles
Temporary Strength loss Mechanically Identical to Shackling Potion, Mangle, Piercing Wail, Crush Under, Dying Star, Monarch's Gaze Strength Down, and Enfeebling Touch.
Knockdown

Knockdown

Debuff Intensity

This creature takes times the damage from other players this turn.

Knockdown
Multiplayer only.
No Block

No Block

Debuff Duration

You cannot gain Block from cards.

(Self) Panic Button
Tag Team

Tag Team

Debuff Intensity

The next Attack another player plays on the enemy is played an extra time.

Tag Team
The Gambit

The Gambit

Debuff Does not stack

If you take unblocked attack damage this combat, die.

(Self) The Gambit
Chains of Binding

Chains of Binding

Debuff Intensity

The first 3 cards drawn each turn are Afflicted with Bound.

Queen
Constrict

Constrict

Debuff Intensity

While the Slithering Strangler is alive, at the end of your turn, take 1 damage.

Slithering Strangler
Dampen

Dampen

Debuff Does not stack

While Magi Knight is alive, ALL your cards are Downgraded.

Magi Knight
Disintegration

Disintegration

Debuff Intensity

At the end of your turn, take 5 damage.

Knowledge Demon, (Self) Disintegration
Hex

Hex

Debuff Does not stack

While Spectral Knight is alive, ALL your cards are Ethereal.

Spectral Knight
Imbalanced

Imbalanced

Debuff Does not stack

If this creature's attacks are fully blocked, it becomes Stunned.

(Self) Bowlbug (Rock)
Magic Bomb

Magic Bomb

Debuff Intensity

Take 20 damage at the end of your turn. Is cleared if the Magi Knight dies.

Magi Knight
Mind Rot

Mind Rot

Debuff Intensity

Draw 1 fewer card each turn.

Knowledge Demon, (Self) Mind Rot
Plow

Plow

Debuff Intensity

The first time this creature's HP reaches 150 or below, it becomes Stunned.

Ceremonial Beast
Ringing

Ringing

Debuff Does not stack

You can only play 1 card this turn.

Ceremonial Beast
Shriek

Shriek

Debuff Intensity

The first time this creature's HP reaches 50% or below, it becomes Stunned.

Terror Eel
Sloth

Sloth

Debuff Intensity

You cannot play more than 3 cards each turn.

Knowledge Demon, (Self) Sloth
Slow

Slow

Debuff Intensity

Whenever you play a card, this enemy receives 10% more damage from Attacks this turn.

Bygone Effigy
Smoggy

Smoggy

Debuff Does not stack

You can only play 1 Skill per turn.

Living Fog
Surrounded

Surrounded

Debuff Does not stack

Receive 50% more damage if attacked from behind. Use targeting cards or potions to change your orientation.

Rocket
Tangled

Tangled

Debuff Intensity

Attacks cost 1 additional Energy this turn.

Vine Shambler
Tender

Tender

Debuff Intensity

Whenever you play a card, lose 1 Strength and 1 Dexterity this turn.

Hunter Killer
Waste Away

Waste Away

Debuff Intensity

Gain 1 less Energy per turn.

Knowledge Demon, (Self) Waste Away

Frequently Asked Questions

What are Powers in Slay the Spire 2?
Powers are persistent effects that last for the remainder of combat once applied. They come in two categories: Buffs (positive effects like Strength, Dexterity, and Artifact) and Debuffs (negative effects like Weak, Vulnerable, and Poison). Powers can be gained from playing Power cards, certain Attacks and Skills, Relics, Potions, or enemy abilities. There are currently 253 unique powers in the game.
What's the difference between Intensity, Counter, and Duration stacking?
Intensity powers grow stronger with each stack — for example, each point of Strength adds 1 damage to every Attack. Counter powers trigger on specific events and consume one stack each time. Duration powers lose one stack at the end of each turn. Some powers do not stack at all, providing a unique persistent effect for the entire combat.
What's the difference between Weak and Vulnerable?
Weak reduces the target's Attack damage by 25%, making it a defensive debuff. Vulnerable causes the target to take 50% more Attack damage, making it an offensive debuff. Both are Duration-type debuffs that lose one stack per turn. Vulnerable is better for aggressive strategies, while Weak is better for survival and longer fights.
How does Intangible work in Slay the Spire 2?
Intangible reduces ALL incoming damage and HP loss to 1 for a number of turns. It's a Duration-type buff that loses one stack at the end of each turn. Intangible is removed at the end of the enemy turn — meaning enemies with Intangible lose it before your next attack phase.
Can Strength go negative in Slay the Spire 2?
Yes, Strength can go negative. Negative Strength reduces your Attack damage by that amount. This can happen when enemies apply Strength Down debuffs or when temporary Strength effects (like Flex Potion) wear off at the end of your turn.
How does Poison work?
Poison is an Intensity-type debuff that deals damage at the start of the poisoned creature's turn, then reduces by 1. Poison stacks additively and scales quadratically with stacks, making it one of the Silent's most powerful damage sources in longer fights.
How does Artifact work?
Artifact is a Counter-type buff that negates incoming debuffs. Each stack of Artifact blocks one debuff application, consuming one stack in the process. A single Artifact stack can absorb any debuff regardless of its intensity.
What does Focus do for the Defect?
Focus is an Intensity-type buff exclusive to the Defect that enhances all Orb effects. Each point of Focus increases Orb passive and evoke values. Focus can go negative — Biased Cognition grants 4 Focus but loses 1 Focus per turn afterward.
Does Feral, Cruelty, or Lethality stack in Slay the Spire 2?
Yes. Feral, Cruelty, and Lethality are all Intensity-type buffs, which means they stack additively. Other Intensity powers that stack include Stampede, Flanking, Void Form, Beacon of Hope, Unmovable, and Accuracy.
Which powers do NOT stack in Slay the Spire 2?
There are currently 37 powers classified as Does Not Stack. These provide a unique persistent effect for the entire combat. Notable examples include Hammer Time, Hellraiser, Barricade, Corruption, and No Draw.
What are Counter-type powers in Slay the Spire 2?
Counter-type powers have a set number of charges consumed when triggered. There are currently 16 Counter powers, all buffs. Examples include Artifact, Buffer, Free Attack, Free Skill, Free Power, and Burst.