Slay the Spire 2 Neow Guide — Boons, Choices & Best Starts
A practical guide to Neow in Slay the Spire 2: what unlocks her, how the boon screen works, and which starts are safest for new runs.
Last updated: March 23, 2026
Quick Answer
Neow is one of the Ancients in Slay the Spire 2. She unlocks after your first run on a save file, then appears at the start of each new run to offer one of three opening boons.
If you are new, prioritize low-risk picks that stabilize Act 1, then scale into higher-risk starts once you are comfortable with pathing and early elite pressure.
All Neow Choices
These choices are data-driven from our relic dataset and mapped by name to Neow's opening pool. Use filters to quickly focus on gold, remove, transform, relic, or risk-heavy starts.
Arcane Scroll
Upon pickup, obtain a random Rare Card to add to your Deck.
Booming Conch
At the start of Elite combats, draw 2 additional cards.
Cursed Pearl
Upon pickup, receive Greed. Gain 333 Gold.
Golden Pearl
Upon pickup, gain 150 Gold.
Large Capsule
Upon pickup, obtain 2 random Relics. Add an additional Strike and Defend to your Deck.
Lava Rock
The Act 1 Boss drops 2 Relics.
Lead Paperweight
Upon pickup, choose 1 of 2 Colorless cards to add to your Deck.
Leafy Poultice
Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose 10 Max HP.
Lost Coffer
Upon pickup, gain 1 card reward and procure 1 random potion.
Massive Scroll
Upon pickup, choose 1 of 3 Multiplayer Colorless Cards to add to your Deck.
Neow's Torment
Upon pickup, add 1 Neow's Fury to your Deck.
New Leaf
Upon pickup, Transform 1 card.
Nutritious Oyster
Upon pickup, raise your Max HP by 11.
Pomander
Upon pickup, Upgrade a card.
Precarious Shears
Upon pickup, remove 2 cards from your Deck and take 13 damage.
Precise Scissors
Upon pickup, remove 1 card from your Deck.
Scroll Boxes
Upon pickup, lose all Gold and choose 1 of 2 packs of cards to add to your Deck.
Silver Crucible
The first 3 card rewards you see are Upgraded. The first Treasure Chest you open is empty.
Small Capsule
Upon pickup, obtain a random Relic.
Stone Humidifier
Whenever you Rest at a Rest Site, raise your Max HP by 5.
No choices matched this filter.
Best Beginner Picks
New players should favor consistency over high-roll variance. In most runs, simple value picks like immediate gold, single-card remove, or clean early upgrades are easier to convert into Act 1 stability than swingy all-in options.
Once your map reading improves, you can lean into riskier choices such as heavy transform or remove lines that trade short-term safety for higher long-term deck quality.
Related pages: Beginner guide (Neow section), Colorless cards, Relics list.